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Vaginal cancer risk

Older age is the main risk factor for cancer. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors.

This page covers other factors with the best evidence of an association with cancer risk; this list is not exhaustive.

See our other pages for general information about cancer, or ways to reduce your risk.

More vaginal cancer statistics

Incidence

Mortality

Survival

Risk

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Acknowledgements

We are grateful to the many organisations across the UK which collect, analyse, and share the data which we use, and to the patients and public who consent for their data to be used.

Find out more about the sources which are essential for our statistics

References

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    Lifetime risk estimates calculated by the Cancer Intelligence Team at Cancer Research UK 2023.

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    Estève J, Benhamou E, Raymond L. Statistical methods in cancer research. Volume IV. Descriptive epidemiology. IARC Sci Publ. 1994;(128):1-302.

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    International Agency for Research on Cancer. List of Classifications by cancer sites with sufficient or limited evidence in humans, Volumes 1 to 122*. Accessed October 2018.

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    Carter JJ, Madeleine MM, Shera K, et al. Human Papillomavirus 16 and 18 L1 Serology Compared across Anogenital Cancer Sites. Cancer Res 2001;61(5):1934-40.

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    Alemany L, Saunier M, Tinoco L, et al. Large contribution of human papillomavirus in vaginal neoplastic lesions: a worldwide study in 597 samples. Eur J Cancer 2014;50(16):2846-54.

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    Parkin DM, Boyd L, Walker LC. 16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010. Br J Cancer 2011;105 Suppl 2:S77-81.

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    Parkin DM. 11. Cancers attributable to infection in the UK in 2010. Br J Cancer 2011;105 Suppl 2:S49-56.

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    Shiels MS, Cole SR, Kirk GD, et al. A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals. J Acquir Immune Defic Syndr 2009;52(5):611-22.

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    Sitas F, Pacella-Norman R, Carrara H, et al. The spectrum of HIV-1 related cancers in South Africa. Int J Cancer 2000;88(3):489-92.

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    Troisi R, Hatch EE, Titus-Ernstoff L, et al. Cancer risk in women prenatally exposed to diethylstilbestrol. Int J Cancer 2007;121(2):356-60.

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    Verloop J, van Leeuwen FE, Helmerhorst TJ, et al. Cancer risk in DES daughters Cancer Causes Control 2010;21(7):999-1007.