General radiotherapy side effects
You might feel tired during your radiotherapy treatment. This could be because:
of the cancer
your body is using energy to repair damage to healthy cells from the radiation
you are in pain
you are having to travel quite a way for your radiotherapy appointments
you're feeling anxious and stressed - this might affect the quality of your sleep at night
Radiotherapy side effects tend to get worse as you progress through your treatment. So you might not feel tired at the beginning of your course but might do towards the end. And for a few weeks afterwards.
It's hard to say who will feel tired during treatment as some do and others don't.
Taking shortcuts on some things or getting help from other people can help you to feel less tired.
Some research into treating tiredness (fatigue) shows that it is important to balance exercise with resting. The amount you do depends on how much you're used to exercising. Pick the time of day when you are feeling least tired.
If you're feeling very tired there are some things you can do to help depending on your circumstances:
Drink plenty of water.
Eat a balanced diet.
Have short naps if you need to.
If you're working, see if you can reduce your hours or work from home if possible.
Ask family and friends for help with things like shopping, housework, gardening, and collecting the children from school.
Don't forget to do things that you enjoy – this may take your mind off things a bit and make you feel more relaxed.
Speak to an occupational therapist or social worker if you have problems with your mobility.
Write a list of shopping and go when the supermarket is not busy or have food delivered.
Do household tasks sitting down, where possible.
If you have children, play games that you can do sitting or lying down. For example, board games, reading books and drawing pictures.
People having radiotherapy for brain tumours often feel tired. This can be worse if you're also taking steroids. The tiredness often reaches its peak 1 to 2 weeks after the end of treatment.
A small number of people are asleep for a lot of the day after a long course of radiotherapy to the brain. This called somnolence syndrome.
You may feel anxious about feeling tired and this is normal. It can help to talk through any worries you have with your doctor, nurse or radiographer.
Find out more information about coping with cancer and tiredness
Last reviewed: 18 Mar 2024
Next review due: 18 Mar 2027
Cancer and its treatment can cause extreme tiredness known as fatigue. There are ways this can be treated.
External radiotherapy uses radiotherapy machines to aim radiation beams at a cancer. This destroys the cancer cells. There are different types of external radiotherapy.
Internal radiotherapy means having radiation treatment from inside the body. It is also called brachytherapy. Read more about what it is and how you have it.
Radiotherapy can cause some general side effects, such as tiredness and skin reactions.
Find out about cancer treatment with radiotherapy, including external radiotherapy, internal radiotherapy, side effects, radiotherapy for symptoms and follow up after treatment.
Search for the cancer type you want to find out about. Each section has detailed information about symptoms, diagnosis, treatment, research and coping with cancer.

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