Metastatic prostate cancer
Metastatic prostate cancer means that a cancer that began in the prostate gland has spread to another part of the body. It is also called advanced prostate cancer.
If your prostate cancer has spread you might:
have bone pain
feel very tired (fatigue)
feel generally unwell
have weight loss for no known reason
You might have specific symptoms depending on where the cancer has spread to. These symptoms can also be caused by other medical conditions. So they might not be a sign that the cancer has spread.
The most common place for prostate cancer to spread to is the bones. It can also spread to the:
liver
lungs
A large tumour in the prostate gland can spread into or press on areas around the prostate, such as the back passage, bladder or .
The most common place for prostate cancer to spread to is the bones. This can include the:
ribs
skull
Find out about treatment for cancer that has spread to the bones
The most common symptom if cancer has spread to the bone is bone pain. It is usually there most of the time and can wake you up at night. The pain can be a dull ache or stabbing pain.
Your bones might also become weaker and more likely to break (fracture).
When prostate cancer spreads to the spine, it can put pressure on the and cause spinal cord compression. This stops the nerves from being able to work properly. Back pain is usually the first symptom of spinal cord compression.
Spinal cord compression is an emergency. You should contact your treatment team immediately if you are worried you might have spinal cord compression.
Lymph nodes are part of a system of tubes and glands in the body that filters body fluid and fight infection.
There are lots of lymph nodes in the pelvic area, which is close to the prostate gland. Prostate cancer can spread to the lymph nodes in the pelvic area, or to other parts of the body.
This might not cause any symptoms. But if it does, it might cause swelling and pain around the area where the cancer has spread.
Cancer cells can stop lymph fluid from draining away. This might lead to swelling in the legs due to fluid build up in that area. The swelling is called lymphoedema.
Large tumours in the prostate can press on the urethra and spread to the bladder. You might find that you:
pass urine more often
get up in the night to pass urine
have difficulty passing urine
have a strong urge to empty your bladder
have blood in your urine or semen
You might have any of the following symptoms if your cancer has spread to the liver:
discomfort or pain on the right side of your tummy (abdomen)
feeling sick
poor appetite and weight loss
a swollen tummy (called ascites)
yellowing of the skin and whites of the eyes (jaundice)
itchy skin
Find out about treatment for cancer that has spread to the liver
You may have any of these symptoms if cancer has spread to your lungs:
a cough that doesn’t go away
breathlessness
coughing up blood
a build up of fluid between the chest wall and the lung (a pleural effusion)
Find out about treatment for cancer that has spread to the lung
The rectum is part of the bowel that is close to the prostate. Prostate cancer can spread to the bowel, but it is rare. You might have:
constipation
pain in your tummy
blood in your poo or from your back passage
There are symptom control teams in most cancer units. They can help you to stay as well as possible for as long as possible. They are also in hospices and many general hospitals.
Most symptom control teams have home care services so they can visit you at home.
Find out about controlling symptoms of prostate cancer
Unfortunately, when prostate cancer has spread to another part of your body, it can no longer be cured. But treatment can control it for some time and help to relieve symptoms.
Finding out that your cancer can’t be cured is distressing and can be a shock. It’s common to feel uncertain and anxious. It's normal not to be able to think about anything else.
Lots of information and support are available to you, your family and your friends. It can help to find out more about your cancer and the treatments you might have. Many people find that knowing more about their situation can help them cope.
Talk to your doctor or nurse to understand:
what your diagnosis means
what is likely to happen
what treatment is available
how treatment can help you
Last reviewed: 21 Jul 2025
Next review due: 21 Jul 2028
Metastatic prostate cancer has spread to other parts of your body. Treatment options include chemotherapy and hormone therapy.
You have a number of tests to check for prostate cancer. These may include a digital rectal examination, a PSA blood test, scans and a biopsy.
Coping with metastatic prostate cancer can be difficult. You might have emotional, practical and physical issues. There is support available.
Prostate cancer can spread to other parts of the body. When this happens, it is called metastatic or advanced prostate cancer.
Survival for prostate cancer is generally good, particularly if you are diagnosed early. Your outlook (prognosis) depends on several factors.
Prostate cancer is cancer that starts in the prostate gland. The prostate gland is found at the base of the bladder and is about the size of a walnut.
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