Cancer Research UK logo.
SearchDonate
  • Search

Diagnosing liver cancer

Screening for liver cancer

There isn’t a national screening programme for  liver cancer in the UK. Primary liver cancer is cancer that starts in the liver. You might have regular checks if you are at high risk of developing it.

What is cancer screening?

Screening means testing people for early stages of a disease. This is before they have any symptoms. For screening to be useful the tests:

  • need to be reliable at picking up cancers

  • overall must do more good than harm to people taking part

  • must be something that people are willing to do

Screening tests are not perfect and have some risks. The screening programme should also be good value for money for the NHS.

Why isn't there a screening programme for liver cancer?

There is no screening programme for liver cancer in the UK because:

  • it's rare so we wouldn't find many cancers

  • there's no suitable test to use for liver cancer screening

  • the cost of screening would be high

Testing for people at high risk of liver cancer

There are some groups of people that are at higher risk of hepatocellular carcinoma (HCC). HCC is the most common type of primary liver cancer.

Your doctor might recommend surveillance if you have:

  • scarring of your liver (liver cirrhosis)

  • long term (chronic) hepatitis B infection

Your doctor will also look at factors such as your age and how much scarring (fibrosis) your liver has.

Find out about the risks and causes of liver cancer

If you are at higher risk, you might have an ultrasound scan every 6 months to check for growths in your liver. You may also have a blood test for AFP (alpha fetoprotein), which can be raised in some people with HCC.

Having these tests regularly can pick up hepatocellular cancers earlier. This means they might be smaller and treatment like surgery or ablation may be possible. 

Speak to your liver specialist at your next check up if you have cirrhosis and are concerned that you're not having tests. 

Read more about tests for primary liver cancer

Last reviewed: 17 Mar 2025

Next review due: 17 Mar 2028

What is liver cancer?

Liver cancer is a cancer that starts in the liver. You might hear it called primary liver cancer.

Symptoms of liver cancer

Symptoms of liver cancer can include weight loss, jaundice, feeling sick, and a swollen or painful tummy (abdomen).

Diagnosing liver cancer

You usually start by seeing your GP. They might refer you for tests or to a specialist if you have symptoms that could be caused by liver cancer.

Risks and causes of liver cancer

Liver cancer is uncommon in the UK. Find out about factors that can increase your risk of developing it.

Liver cancer main page

Primary liver cancer is cancer that started in the liver. This section is mainly about the most common type of liver cancer, hepatocellular carcinoma (HCC).

Secondary liver cancer

Secondary liver cancer is when a cancer that started somewhere else in the body has spread to the liver. It is also called liver metastases.

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and Support

An icon of a hand shake.

Questions for your doctor

What to ask your doctor about clinical trials.

An icon of two speech bubbles, indicating a conversation.

Cancer chat forum

Meet and chat to other cancer people affected by cancer.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.