Infections
Infections can sometimes be life threatening. A fever may be the first or only sign of an infection. But with some infections, you may have other symptoms without a fever.
Treating an infection early can stop it becoming a more serious problem. Tell your healthcare team immediately about any symptoms. Even if it turns out that you don’t have an infection it’s better to find out as soon as possible.
There are several symptoms you might have when you have an infection. Call your 24 hour advice line straight away if you have any of these:
feeling generally unwell – not able to get out of bed
a temperature of 37.5°C or above
a temperature below 36°C
flu-like symptoms – feeling cold and shivery, headaches, and aching muscles
coughing up green phlegm
a sore throat or sore mouth
a throbbing, painful tooth
pain having a wee, going more often or cloudy or foul-smelling wee
diarrhoea – 4 or more loose, watery bowel movements in 24 hours
skin changes – redness, feeling hot, swelling or pain
a fast heartbeat
feeling dizzy or faint
being sick (vomiting)
a headache
pain, redness, discharge, swelling or heat at the site of a wound or intravenous line such as a central line or PICC line
pain anywhere in your body that was not there before your treatment
It is important to start treatment if it’s needed as soon as possible. This reduces the risk of an infection developing into sepsis.
Sepsis is a serious complication of an infection that can be life threatening.
The following symptoms could be due to sepsis. Call 999 or go to your local Accident and Emergency (A&E) immediately if you have any of the following:
Slurred speech or confusion
Extreme shivering or muscle pain
Passing no urine (in a day)
Severe breathlessness
It feels like you’re going to die
Skin mottled or discoloured
Some types of painkillers such as paracetamol and ibuprofen are anti pyretics. This means they bring down temperatures. Taking these may disguise that you have an infection. Taking steroids can also hide the signs of infection.
A fever in itself is not usually dangerous, but the infection that causes it can be.
An infection can occur anywhere in your body. The most common places are:
the mouth and throat
the skin
the lungs
the kidneys and bladder, especially if you have a catheter to drain urine from your bladder
where a drip or central line goes in (cannula sites and PICC line sites)
wounds and where wound drains go in
ulcerating tumours
the bloodstream
liver and abdomen
gullet (oesophagus)
vagina
anus
brain and spinal cord
You can’t always prevent an infection. The most important thing you can do is contact your advice line, or depending on your symptoms – call 999 or go to A&E. But there are things you can do to help yourself and reduce your risk of getting an infection.
Before Treatment
Have a dental check.
Buy a thermometer and make sure you and your friends and family know how to use it.
Talk to your healthcare team about vaccines you should have. For example, the flu vaccine and Coronavirus (COVID-19) vaccine.
Make sure you and your family and friends are familiar with the symptoms of an infection and sepsis. Let everyone know about the advice line.
Your hospital may give you an alert card explaining the symptoms and what to do.
During treatment
Try to avoid people who are unwell or have an infection. For example, people with chest infections, diarrhoea, and chicken pox.
Brush your teeth with a soft toothbrush at least twice a day and preferably after every meal and at bedtime.
Tell your doctor if you have any ulcers or pain anywhere in your mouth.
Wash your hands before eating or handling food, after using the toilet, and after contact with animals.
Protect your skin from scratches. You can do this by wearing gloves and keeping your arms and legs covered when you are gardening. If you do cut or graze your skin, wash the area thoroughly with warm water and soap. You can put antiseptic cream over the area and cover it with a plaster.
Store, prepare, and cook food following the correct instructions.
Read about possible infections during or after cancer treatment
Don’t be afraid to live your life as normal. You do not need to stop seeing family and friends unless they have an infection or feel unwell. You don't need to avoid crowded places unless specifically advised to do so by your healthcare team.
Treatment depends on the type of infection you have. We have a section on treating fever and infection.
Last reviewed: 12 Feb 2023
Next review due: 12 Feb 2026
Cancer and cancer treatments can make it more likely for you to get an infection. There are many different types of infections.
Treating a fever depends on what is causing your fever. Treating the symptoms of fever can also help you feel more comfortable.
A number of things can cause fever. This can include some cancers, drugs, and other treatments.
Sepsis is a serious complication of an infection that can be life threatening. Fever might be the first sign of an infection, or you might have other symptoms.

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