Cancer Research UK logo.
SearchDonate
  • Search

Tests and scans

Needle biopsy through the skin for lung cancer

This test is also called a percutaneous lung biopsy. A doctor called a radiologist takes a sample of lung tissue by passing a needle into the lung. They use a CT scanner or ultrasound to ensure they know the right place to take the sample.

You have this test with a . It takes about 30 to 45 minutes.

Diagram showing the lungs including the apex.

Why do I need a biopsy through the skin?

You might have this test if your doctor has seen an abnormal looking area in your lung or airways using an x-ray or CT scan.

What do I need to do to prepare for a biopsy through the skin?

You’ll be given written instructions on how to prepare for your biopsy through the skin. For example, they will ask you not to eat and drink for a few hours before the test.

Take your usual medicines as normal unless your doctor tells you otherwise. If you take warfarin or other blood thinners to thin your blood, you need to stop this before your test. Your doctor will tell you when to stop them.

What happens on the day?

Before the test

When you arrive at the outpatient department the nurse takes some measurements. This includes your blood pressure, heart and breathing rate, your oxygen level and weight.

You’ll see your radiologist who will explain what’s going to happen and ask you to sign a consent form. This is a good time to ask any questions you may have.

You may need to change into a hospital gown, or you might be able to stay in your own clothes.

Having a local anaesthetic

The nurse takes you to the test room. You have the procedure on a couch, lying down in the best position for taking the biopsy.

The radiologist will clean your skin with antiseptic fluid and numb it with a local anaesthetic. The local anaesthetic used to numb the area may sting for a few seconds, but once this is working, you will not feel anything in that area.  

Attached to one of your fingers is a clip to monitor your heart rate and oxygen levels throughout the test.

During the test

A scan will be taken using a small metallic marker on the outside of your skin. This marker shows up in the scan images. It helps the radiologist decide the best place to take the biopsy.

The radiologist will ask you to hold your breath while they put a fine needle through your skin and into your lung to take the biopsy. You may feel some pressure from the biopsy needle as it takes the sample. The radiologist takes out some tissue through the needle and into a syringe. They may have to repeat this part of the test 2 to 3 times to take a good sample. 

They send the tissue to a laboratory. A pathologist then looks at the tissue down a microscope to see exactly what the abnormality is.

During the test, your nurse or anaesthetist will check your oxygen levels and heart rate using the clip on your finger.

The test takes about 30 to 45 minutes.

Diagram showing a percutaneous lung biopsy .

After your biopsy

You might need to stay in hospital overnight. 

You go back to the ward so you can rest. You can eat and drink as usual.

Your nurse monitors you closely for a few hours. They check your heart rate and oxygen levels using a clip on your finger. This doesn’t hurt. They check your blood pressure regularly, using a cuff on your arm. Your nurse makes sure any pain you have is under control. Ask for painkillers if you need them.

You usually have a chest x-ray 3 or 4 hours after the biopsy.

Going home

You have a waterproof dressing over your biopsy site. Your nurse will tell you how to look after the dressing over the next few days.

You need to take things easy for a few days after the biopsy.

Possible risks

The possible risks include:

Bleeding

You might see a small amount of blood in your spit after the test. Let your doctor or nurse know if this doesn’t go away.

Chest infection

See your doctor straight away if your phlegm (sputum) changes colour, you feel more breathless or feel as though you have a temperature. Tell them if the dressing over the biopsy site has lots of ooze on it.

Needing extra oxygen

You might need oxygen through a mask for a while after the biopsy. If you normally have oxygen at home you might need to have more than usual for a time.

A collapsed lung (pneumothorax)

Air or gas can collect in the space around the lung and make it collapse, but this is rare. Contact a doctor if you become short of breath or have chest pain. You have a tube put into the lung to remove the air.

Let your doctor know if you are due to fly soon after your biopsy. They can give you advice about how long you should wait before taking a flight.

Getting your results

You should get your results within 1 or 2 weeks. Contact your doctor if you haven’t heard anything after this time.

Waiting for test results or for further tests can be very worrying. You might have contact details for a specialist nurse and you can contact them for information if you need to. It may help to talk to a close friend or relative about how you feel.

More information

You can read more information about other tests to help doctors diagnose lung cancer.

Tests to diagnose lung cancer

Last reviewed: 28 Dec 2022

Next review due: 28 Dec 2025

Getting diagnosed with lung cancer

You usually start by seeing your GP, and they might refer you to a specialist and organise tests. Or you might be referred to a specialist and further tests if screening for lung cancer or a lung health check showed that you might have lung cancer.

Stages and types of lung cancer

The stage of a cancer tells you how big it is and whether it has spread. The type tells which type of cell the cancer started from.

Treatment for lung cancer

Your treatment depends on several factors. These include what type of lung cancer you have, how big it is and whether it has spread (the stage). It also depends on your general health.

What is lung cancer?

Lung cancer starts in the windpipe (trachea), the main airway (bronchus) or the lung tissue. Cancer that starts in the lung is called primary lung cancer.

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and Support

An icon of a hand shake.

Questions for your doctor

What to ask your doctor about clinical trials.

An icon of two speech bubbles, indicating a conversation.

Cancer chat forum

Meet and chat to other cancer people affected by cancer.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.