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Treatment for prostate cancer

High intensity focused ultrasound (HIFU) for prostate cancer

HIFU is a treatment that uses high frequency sound waves to destroy prostate cancer cells. The waves create heat that destroys the cancer cells.

You might have HIFU for prostate cancer that hasn’t spread outside the prostate gland. Or for prostate cancer that has come back in the prostate after treatment. It is only available in specific centres in the UK or as part of a clinical trial. 

Find out about research looking into treatment for prostate cancer

What is HIFU?

HIFU stands for high intensity focused ultrasound. It is a treatment that uses high frequency sound waves.

You have HIFU from a machine. The machine gives off sound waves. These deliver a strong beam to the cancer. This heats up and destroys the prostate cancer cells.

You might have HIFU treatment to either:

  • the whole prostate gland - this is whole prostate HIFU

  • specific areas of the prostate gland - this is focal HIFU

Who can have HIFU?

The National Institute for Health and Care Excellence (NICE) is an independent organisation. It provides guidance to the NHS and develops recommendations about treatment. NICE recommends HIFU for prostate cancer only in specific centres or as part of clinical trials. 

Your doctor might recommend HIFU if your cancer:

  • is contained inside the prostate gland - this is localised prostate cancer

  • is just breaking through the covering of the prostate - this is locally advanced prostate cancer

  • has come back after earlier treatment - this is salvage treatment

You can’t have HIFU if your cancer has spread to other parts of your body. This is metastatic or advanced prostate cancer.

Before your treatment

Check your appointment letter for any specific ways to prepare for HIFU.

You have HIFU treatment at the hospital as a day patient. This means you can usually leave on the same day that you have HIFU. Your doctor asks you to sign a consent form to say that you agree to have the treatment. This is a good time to ask all the questions that you have.

You might have an  or before the treatment. This is to find the exact position of the cancer so doctors can plan your treatment.

You have an to empty your bowels.

You have this treatment under . You usually need to stop eating for 6 hours before the procedure but can still drink fluids. Your healthcare team will tell you when to stop drinking.

You change into a hospital gown before the procedure.

During HIFU

You have HIFU in the operating theatre under general anaesthetic. This means that you are asleep and won’t feel anything. You have a small tube (cannula) in a vein in the back of your hand.

Your surgeon puts a thin tube into your bladder through your  . The tube drains your urine. It is called a urinary catheter.

Diagram showing a catheter.

Your surgeon puts a HIFU probe into your . This probe gives out high intensity ultrasound waves that can destroy the cancer cells in your prostate. The high intensity ultrasound waves travel through the rectum to the prostate. The waves do not destroy tissue on their way. They only damage the cells in the tissue they are targeting. 

The probe also works as an ultrasound and makes a picture on a screen. This shows your surgeon where they need to target. They move the HIFU probe around to treat all of the cancer cells.

Diagram showing high intensity focused ultrasound (HIFU) for prostate cancer.

Whole prostate HIFU treatment takes about 3 hours. HIFU to a smaller area (focal HIFU) takes 1 to 2 hours. 

When you are fully awake you go back to the ward to rest. The nurses check on whether you have any pain and will give you painkillers if you need them.

After your treatment

When you have recovered from the anaesthetic you can go home, usually on the same day. You won’t be able to drive home after the general anaesthetic. This is because it takes some time for the anaesthetic to wear off.

You might have a catheter for up to a week to drain urine. If you go home with a catheter your nurse will teach you how to care for it. They will arrange for someone to remove it.

Side effects of HIFU

Your doctor explains all the potential side effects to you before you sign the consent form.

All treatments have side effects and it’s important that you know about them before HIFU. You might have some of these side effects.

Pain

You might have pain in the area between your testicles and back passage (rectum). You can take painkillers to help.

Blood in your urine

You might have some blood or small pieces of prostate tissue in your urine. This can last for a few weeks.  

Erection problems

At first you might have difficulty having or keeping an erection. For many men this goes back to normal. Treatments can help with erection problems.

Find out about treatments for erection problems

Urine infection

Signs of a urine infection include pain passing urine or feeling cold or shivery.

Contact your treatment centre straight away if you have any of these signs or if your temperature goes above 38°C. Severe infections can be life threatening. 

Problems passing urine

You might have problems passing urine if the prostate swells after HIFU. The swelling can block the urethra. This might happen straight after removing your catheter. It is called urinary retention.

You might need to have a catheter for a short time to drain the urine.

You doctor may suggest that you learn how to put in a catheter to drain your urine at home. This is called self catheterisation. You take the catheter out when the bladder is empty. Your nurse will teach you how to do this.

Read more about problems passing urine after prostate cancer treatment

Infection in your testicles

Infection can start in the small tubes that carry sperm from the testicles. You might have:

  • swelling in one or both of your testicles

  • pain or tenderness in one or both of your testicles

Tell your doctor or nurse if you have swelling or pain. You might need antibiotic tablets.

Long term side effects

Possible long term side effects include:

  • erection problems

  • loss of control of urine (urinary incontinence)

  • problems passing urine due to blockage of the urethra

  • a hole between the bladder and the back passage – this is rare

HIFU and clinical trials

HIFU is not available in every hospital. Your doctor might offer you HIFU treatment as part of a clinical trial. Or you might need to travel to specialist centre for treatment.

Find out about prostate cancer clinical trials

Last reviewed: 11 Jul 2025

Next review due: 11 Jul 2028

Treatment for prostate cancer

You may have a choice of treatments such as surgery or radiotherapy. Or your doctor might suggest that they monitor your cancer instead of treatment straight away.

Research and clinical trials for prostate cancer

Research is looking into diagnosing and treating prostate cancer. You need to talk to your specialist if there are any trials that you think you might be able to take part in.

Treatment options for prostate cancer

Your specialist doctor discusses whether you need treatment, and what your treatment options are. Treatment options might include surgery or radiotherapy.

Metastatic prostate cancer treatment

Metastatic prostate cancer has spread to other parts of your body. Treatment options include chemotherapy and hormone therapy.

Living with prostate cancer

Get practical and emotional support to help you cope with a diagnosis of prostate cancer, and life during and after treatment.

Prostate cancer main page

Prostate cancer is cancer that starts in the prostate gland. The prostate gland is found at the base of the bladder and is about the size of a walnut.

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