Non-Hodgkin Lymphoma
The most common symptom of non-Hodgkin lymphoma (NHL) is one or more painless swellings in the:
neck
armpit
groin
These swellings are enlarged lymph nodes.
You might have other general symptoms such as:
heavy sweating at night
temperatures that come and go with no obvious cause
losing a lot of weight (more than one tenth of your total weight over 6 months) and you don't know why
Doctors call this group of symptoms B symptoms. Some people with NHL have these symptoms, but many don't.
Doctors assess whether you have B symptoms to your NHL and plan your treatment.
There can be many other symptoms depending on where your NHL is in the body. These include:
enlarged tonsils (these are at the back of your throat)
a lump in your tummy due to an enlarged liver or spleen or lymph nodes - you may feel full after only a small amount of food, feel sick or have tummy pains
breathlessness, chest pain or a feeling of pressure, or coughing - if lymphoma is affecting nodes in your chest
unexplained itching
Other symptoms can be caused by enlarged lymph nodes pressing on an organ, nerve or blood vessel.
Lymphomas that start in other organs, such as the stomach or skin, might cause symptoms such as weight loss or skin rashes.
Some people with NHL have lymphoma cells in their bone marrow when they are diagnosed. This can cause low blood cell counts, such as:
low red blood cell counts (anaemia), causing tiredness and sometimes breathlessness
low white blood cell counts, increasing your risk of getting infections
low platelet counts, causing bleeding problems such as very heavy periods, nosebleeds, unexplained bruising or a rash of tiny blood spots under the skin
Lymphoma that starts in the brain is called primary cerebral lymphoma or primary central nervous system (CNS) lymphoma. This is very rare. It can cause symptoms such as:
headaches
difficulty thinking
difficulty moving parts of the body
changes in personality
changes to speech
epileptic fits (seizures)
High grade lymphomas that started elsewhere in the body can sometimes spread to the brain. If this happens, you may have similar symptoms to these.
Last reviewed: 14 Feb 2024
Next review due: 14 Feb 2027
Non-Hodgkin lymphoma (NHL) is a type of blood cancer that affects white blood cells called lymphocytes. It's the 6th most common type of cancer in adults.
You usually start by seeing your GP. They might refer you to a specialist doctor (haematologist) and organise tests.
Your treatment depends on the type and stage of your NHL. Common treatments include chemotherapy, targeted and immunotherapy drugs, radiotherapy and a stem cell transplant.
The stage tells you about the number and places in your body that are affected by lymphoma. There are 4 stages for NHL. Or doctors describe it as either early or advanced stage.
Practical and emotional support is available to help you cope with non-Hodgkin lymphoma.

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