Metastatic lung cancer
Metastatic lung cancer means that the cancer has spread from where it started in the lung. It is also called advanced lung cancer.
It might not mean that you have advanced cancer if you have the symptoms described below. They can be caused by other conditions.
Possible symptoms of lung cancer are:
a new cough or a cough most of the time
breathlessness
unexplained weight loss
a chest infection that won't go away or keeps coming back
coughing up blood
a hoarse voice
difficulty swallowing
changes in the shape of your fingers and nails called finger clubbing
swelling of the face caused by a blockage of a main blood vessel (superior vena cava obstruction)
a loss of appetite
tiredness and weakness
Your doctor might carry out routine blood tests and find that you have a raised platelet count (thrombocytosis). This might be a sign of lung cancer but could also be due to other illnesses or conditions.
The pleura or pleural membranes are 2 fibrous sheets of tissue. They cover the lungs and help to protect them. Lung cancer can sometimes cause a build up of fluid between the pleura. This is called a pleural effusion. This can cause a cough and breathlessness.
You may feel very breathless if the cancer is blocking your airway or if there is fluid around your lung.
Find out about coping with breathlessness
Other symptoms of metastatic lung cancer depend on where the cancer is in the body. Lung cancer can spread to:
the nearby or distant lymph nodes
the brain
the liver
the bones
the
other parts of the lung or the other lung
The lymph nodes are part of a system of tubes and glands in the body that filters body fluid and fight infection.
The most common symptom if cancer has spread to the lymph nodes is that they are bigger than normal. But lymph nodes also get bigger if you have an infection. So you can't be sure of the cause of a lump until your doctor has examined you and done some tests.
Tell your doctor if you find any lumps or swollen areas, particularly in your neck or armpits.
Cancer that has spread to the brain might cause any of the following symptoms:
memory problems, mood or personality changes
seizures
confusion
severe headaches, often with sickness
weakness of an arm or leg
You might have any of the following symptoms if your cancer has spread to the liver:
discomfort or pain on the right side of your tummy (abdomen)
feeling sick
poor appetite and weight loss
a swollen tummy (called ascites)
yellowing of the skin and whites of the eyes (jaundice)
itchy skin
Find out about cancer that has spread to the liver
Cancer that has spread to the bone can cause:
pain - this can be lower back pain if the cancer cells are in the spinal bones
weaker bones - they may get damaged or break more easily
raised calcium levels in your blood - causing dehydration and confusion
If you have these symptoms, you may have a scan or a .
Sometimes cancer cells in the spinal bones can press on the spinal cord. This is called spinal cord compression. It can cause:
weakness in your legs
numbness
loss of bladder or bowel control
Find out about cancer that has spread to the bone
The adrenal glands are small glands just above the kidney.
Cancer that has spread to the adrenal glands doesn’t usually cause any symptoms.
The adrenal glands produce hormones and if cancer has spread to both adrenal glands you might have low levels of adrenal hormones. This might cause:
loss of appetite
weight loss
nausea
tummy (abdominal) pain
weakness
changes to substances in your blood
Some people have swollen fingers and nails, and pain and swelling in their joints. This condition is called hypertrophic pulmonary osteoarthropathy (HPOA).
Treatments such as radiotherapy or chemotherapy can sometimes shrink the cancer and reduce symptoms.
Find out about controlling symptoms
Your doctor or specialist nurse can:
give you medicines
help you to get the equipment that you need
suggest other ways of controlling your symptoms
refer you to a symptom control team (a palliative care team)
There are symptom control teams in most cancer units. They can help you to stay as well as possible for as long as possible. They are also in hospices and many general hospitals.
Most symptom control teams have home care services so they can visit you at home.
Last reviewed: 10 Oct 2025
Next review due: 10 Oct 2028
Metastatic lung cancer means that a cancer that began in the lung has spread to another part of the body.
Your treatment depends on several factors. These include what type of lung cancer you have, how big it is and whether it has spread (the stage). It also depends on your general health.
There is support available during and after treatment to help you cope. This includes support from your clinical nurse specialist, cancer charities, community services, and family and friends.
Coping with lung cancer can be difficult. There are things you can do and specialists who can help you to cope with a diagnosis of lung cancer or metastatic lung cancer.
Feeling short of breath can be hard to live with. It can make you feel tired and like everything is a struggle. But some things can help you to cope.
Lung cancer starts in the windpipe (trachea), the main airway (bronchus) or the lung tissue. Cancer that starts in the lung is called primary lung cancer.

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